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Analysis of STRs shows that


A) the more alleles that are analyzed, the more frequent the combinations become in a population.
B) the more alleles that are analyzed, the rarer the combinations become in a population.
C) all STR alleles occur at equal frequency..
D) the usefulness of STRs for DNA profiling is very limited.
E) None of these are correct.

F) A) and C)
G) All of the above

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DNA analysis of evidence at a crime scene matches the STR pattern of an individual in the CODIS database but the suspect says that he did not commit the crime.He claims that it must have been his twin sister.Explain why his argument is not valid.

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Based on assumptions behind testing and ...

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Which of the following DNA elements have NOT been used to develop DNA profiles?


A) minisatellites
B) STRs
C) RFLPs
D) telomeres
E) All of these have been used to develop DNA profiles.

F) C) and E)
G) A) and D)

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DNA profiles have been developed from the remains of dead people.

A) True
B) False

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True

What was the first U.S.court case to challenge the admissibility DNA evidence?


A) Frye v. U.S.
B) People v. Castro
C) Narborough Village Murders
D) Jennifer Thompson-Canino v. Ronald Cotton
E) Margaret Sackler v. William Bern

F) B) and E)
G) D) and E)

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All STRs are located on the X chromosome.

A) True
B) False

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The polymerase chain reaction (PCR) uses ____ to amplify a particular stretch of DNA.


A) DNA polymerase
B) RNA polymerase
C) restriction enzymes
D) ribosomes
E) repeated sequences

F) B) and E)
G) B) and D)

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Which of the following statements about haplotypes is FALSE?


A) Haplotype analysis can provide information about ancestry.
B) Each person has the same mtDNA haplotype as his or her mother.
C) Y chromosomal haplotypes can be used to trace paternal lineage.
D) Haplotypes are based on differences in DNA sequence.
E) Haplotypes analysis is only useful to determine paternity.

F) C) and D)
G) A) and C)

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E

Why are minisatellites important for DNA analysis?


A) They are useful for determining the sex of the criminal.
B) Variation in the number of repeats is used in preparing DNA profiles.
C) They are used when there is no DNA available to analyze.
D) They can help geneticists determine the inheritance pattern of a trait.
E) Data from minisatellite analysis is stored in the FBI database.

F) None of the above
G) A) and D)

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MATCHING Match the appropriate term with the description. -haplotypes


A) useful for tracking maternal ancestry
B) passed only from fathers to sons
C) information stored in CODIS
D) a series of specific DNA markers
E) repeated sequences of 10-100 base pairs in length
F) DNA differences that are only one base pair long
G) method to make many copies of a segment of DNA
H) analysis using restriction enzymes

I) A) and F)
J) A) and D)

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A DNA sample from an individual is analyzed.The population frequency of one of the STR alleles is 1 in 50,a second STR allele is 1 in 100,and a third STR allele is 1 in 30.What is the combined frequency of these three STR alleles?


A) 1 in 150,000
B) 1 in 15,000
C) 1 in 1,500
D) 1 in 180
E) 1 in 50

F) All of the above
G) A) and E)

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Do you think mandatory DNA profiling should be done for all U.S.military personnel? Why or why not? Could this mandatory profiling be considered a violation of the individual's human rights? Explain your answer.

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Answers will vary but the utility of usi...

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When an electric current is passed through an agarose gel,the migration of DNA fragments through the gel is based on the number of copies of each fragment.

A) True
B) False

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False

Various recommendations have been made concerning DNA profiling of all persons who have committed a felony.Would you consider this a violation of the individual's human rights? Indicate how this type of information could be useful in locating and identifying criminals implicated in future assaults and rapes and in the associated court cases?

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Answers will vary as to the human rights...

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Two common techniques used in DNA forensics are restriction fragment length polymorphism analysis and the polymerase chain reaction.

A) True
B) False

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MATCHING Match the appropriate term with the description. -RFLPs


A) useful for tracking maternal ancestry
B) passed only from fathers to sons
C) information stored in CODIS
D) a series of specific DNA markers
E) repeated sequences of 10-100 base pairs in length
F) DNA differences that are only one base pair long
G) method to make many copies of a segment of DNA
H) analysis using restriction enzymes

I) G) and H)
J) E) and G)

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Analysis of mtDNA or Y chromosomes provides data that allows people to trace their ancestry.

A) True
B) False

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Which of the following statements about STRs is FALSE?


A) They are only 2-9 bases long.
B) Clusters are found widely distributed on all human chromosomes.
C) Variation in the number of repeats is used in preparing DNA profiles.
D) They consist of differences in DNA sequences that are only one nucleotide long.
E) They consist of short repeated nucleotide sequences.

F) B) and E)
G) A) and E)

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____ are repeated sequences of 10-100 base pairs that are used for developing DNA profiles.


A) Minisatellites
B) STRs
C) RFLPs
D) SNPs
E) Mitochondrial DNA

F) C) and D)
G) D) and E)

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DNA fragments are separated in an agarose gel based on


A) size, with the shortest DNA fragments traveling farthest.
B) size, with the longest DNA fragments traveling the farthest.
C) the presence or absence of certain SNPs.
D) the number of strands in the DNA fragments.
E) the frequency of particular DNA nucleotides.

F) A) and B)
G) A) and C)

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